TWiV 674: In the company of coronaviruses with Lisa Gralinski

<div class="entry-content"> <p>Lisa joins TWiV to discuss her research on the pathogenesis of SARS-CoV, MERS-CoV, and SARS-CoV-2, including work on vaccines and an antiviral, then we review the SARS-CoV-2 spike protein as a potential analgesic, and listener questions.</p> <p>Hosts: <a href= "http://en.wikipedia.org/wiki/Vincent_Racaniello">Vincent Racaniello,</a> <a href= "http://www.mgm.ufl.edu/faculty/faculty-home-pages/condit-richard-c/"> Rich Condit</a>, <a href= "https://sites.google.com/a/umich.edu/spindler-lab/">Kathy Spindler</a> and <a href= "http://www.twitter.com/BioProfBarker">Brianne Barker</a></p> <p>Guest: <a href= "https://sph.unc.edu/adv_profile/lisa-gralinski-phd/">Lisa Gralinski</a></p> <p>Subscribe (free): <a href= "http://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?id=300973784">iTunes</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aXYubWljcm9iZXdvcmxkLmxpYnN5bnByby5jb20vdHdpdg%3D%3D">Google Podcasts</a>, <a href= "http://twiv.microbeworld.libsynpro.com/twiv">RSS</a>, <a href="http://eepurl.com/Gcw59">email</a></p> <p>Become a <a href= "https://www.microbe.tv/contribute">patron</a> of TWiV!</p> <h3><strong>Links for this episode</strong></h3> <ul> <li>SARS-like bat CoV with potential for <a href= "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797993/">human emergence</a> (Nat Med)</li> <li>SARS-CoV <a href= "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599853/">susceptibility loci</a> in CC mice (PLoS Genetics)</li> <li>Combination attenuation for <a href= "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096805/">SARS-CoV vaccine</a> (J Virol)</li> <li><a href= "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523135/">Orally administered</a> SARS-CoV-2 antiviral (Res Sq)</li> <li>Spike protein induces <a href= "https://journals.lww.com/pain/Abstract/9000/SARS_CoV_2_Spike_protein_co_opts.98244.aspx"> analgesia</a> (Pain)</li> <li><a href="https://www.microbe.tv/twiv/twiv-674-letters/">Letters read</a> on TWiV 674</li> <li>Timestamps by <a href= "http://www.twitter.com/j