TWiV 954: Speculating sarbecovirus spillovers with Michael Letko

<p>Michael Letko joins TWiV to discuss his research on understanding cell receptors required for sarbecovirus entry, including an ACE2-dependent isolate from Russian bats that is resistant to vaccine-induced antibodies.</p> <p>Hosts: <a href= "http://en.wikipedia.org/wiki/Vincent_Racaniello">Vincent Racaniello</a>, <a href="http://trichinella.org/">Dickson Despommier</a>, <a href= "http://mgm.ufl.edu/profile/condit-rich/">Rich Condit</a>,  <a href= "https://sites.google.com/a/umich.edu/spindler-lab/">Kathy Spindler</a>, and <a href= "http://twitter.com/bioprofbarker">Brianne Barker</a></p> <p>Guest: <a href= "https://scholar.google.com/citations?user=7NRXfk0AAAAJ&hl=en">Michael Letko</a></p> <p>Subscribe (free): <a title= "http://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?id=300973784" href= "https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065">Apple Podcasts</a>, <a href= "https://www.google.com/podcasts?feed=aHR0cDovL3R3aXYubWljcm9iZXdvcmxkLmxpYnN5bnByby5jb20vdHdpdg%3D%3D">Google Podcasts</a>, <a href= "http://twiv.microbeworld.libsynpro.com/twiv">RSS</a>, <a href="http://eepurl.com/Gcw59">email</a></p> <p>Become a <a href= "https://www.microbe.tv/contribute">patron</a> of TWiV!</p> <h3 id="links-for-this-episode">Links for this episode</h3> <ul> <li>Support MicrobeTV with a Spike t-shirt (<a href= "https://vaccinated.us/">Vaccinated.us</a>) with promo code MicrobeTV</li> <li><a href="https://pubmed.ncbi.nlm.nih.gov/32094589/">Cell entry</a> of SARS-CoV-2 and other sarbecoviruses (Nat Micro)</li> <li>ACE2-dependent sarbecovirus in <a href= "https://pubmed.ncbi.nlm.nih.gov/36136995/">Russian bats</a> (PLoS Path)</li> <li><a href="https://www.microbe.tv/twiv/twiv-954-letters/">Letters read</a> on TWiV 954</li> <li>Timestamps by <a href= "http://www.twitter.com/jrrmicro">Jolene</a>. Thanks!</li> </ul> <h3>Weekly Picks</h3> <p><strong>Brianne</strong> – <a href= "https://www.nytimes.com/2022/11/09/science/octopus-throwing-silt.html"> Sometimes This Octopus is So Mad it Just Wants to