TWiV 887: Bonfire of the monocytes

<p>TWiV explains why this season’s influenza vaccine is not protecting against mild to moderate disease caused by H3N2 virus, and that antibody-dependent entry of SARS-CoV-2 into monocytes is a major contributor to severe COVID-19.</p> <p>Hosts: <a href= "http://en.wikipedia.org/wiki/Vincent_Racaniello">Vincent Racaniello</a>, <a href="http://trichinella.org/">Dickson Despommier</a>, <a href= "http://mgm.ufl.edu/profile/condit-rich/">Rich Condit</a>, and <a href="http://enterovirus.net/">Amy Rosenfeld</a></p> <p>Subscribe (free): <a title= "http://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?id=300973784" href= "https://podcasts.apple.com/us/podcast/this-week-in-virology/id1176779065">Apple Podcasts</a>, <a href= "https://www.google.com/podcasts?feed=aHR0cDovL3R3aXYubWljcm9iZXdvcmxkLmxpYnN5bnByby5jb20vdHdpdg%3D%3D">Google Podcasts</a>, <a href= "http://twiv.microbeworld.libsynpro.com/twiv">RSS</a>, <a href="http://eepurl.com/Gcw59">email</a></p> <p>Become a <a href= "https://www.microbe.tv/contribute">patron</a> of TWiV!</p> <h3 id="links-for-this-episode"><strong>Links for this episode</strong></h3> <ul> <li>Seasonal influenza <a href= "https://www.cdc.gov/mmwr/volumes/71/wr/mm7110a1.htm">vaccine effectiveness</a> (MMWR)</li> <li>Properties of a dominant <a href= "https://www.medrxiv.org/content/10.1101/2021.12.15.21267857v1">H3N2 variant</a> (bioRxiv)</li> <li>Scott Henley on influenza vaccine growth in eggs (<a href= "https://www.microbe.tv/twiv/twiv-480/">TWiV 480</a>)</li> <li>Fc receptor dependent entry of <a href= "https://www.nature.com/articles/s41586-022-04702-4">SARS-CoV-2 into monocytes</a> (Nature)</li> <li>Timestamps by <a href= "http://www.twitter.com/jrrmicro">Jolene</a>. Thanks!</li> </ul> <h3 id="weekly-picks-1-34-06">Weekly Picks</h3> <p><strong>Dickson</strong> – <a href= "https://www.yahoo.com/news/ketanji-brown-jackson-confirmed-supreme-191014333.html"> Ketanji Brown Jackson confirmed to US Supreme Court</a><br /> <strong>Amy</strong> – <a href= "https://www.theatlantic.com/ideas/a