TWiV 715: Fauci ouchy

<div class="entry-content"> <p>TWiV explains why hydroxychloroquine failed in humans despite showing antiviral effects in cells, and reviews the published data on the Pfizer/BioNTech mRNA vaccine.</p> <p>Hosts: <a href= "http://en.wikipedia.org/wiki/Vincent_Racaniello">Vincent Racaniello,</a> <a href= "http://www.mgm.ufl.edu/faculty/faculty-home-pages/condit-richard-c/"> Rich Condit</a>, <a href= "https://sites.google.com/a/umich.edu/spindler-lab/">Kathy Spindler</a>, and <a href= "http://twitter.com/bioprofbarker">Brianne Barker</a></p> <p>Subscribe (free): <a href= "http://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?id=300973784">iTunes</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL3R3aXYubWljcm9iZXdvcmxkLmxpYnN5bnByby5jb20vdHdpdg%3D%3D">Google Podcasts</a>, <a href= "http://twiv.microbeworld.libsynpro.com/twiv">RSS</a>, <a href="http://eepurl.com/Gcw59">email</a></p> <p>Become a <a href= "https://www.microbe.tv/contribute">patron</a> of TWiV!</p> <h3><strong>Links for this episode</strong></h3> <ul> <li>TMPRSS2 is why <a href= "https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1009212"> hydroxychloroquine failed</a> (PLoS Path)</li> <li>Safety and efficacy of <a href= "https://www.nejm.org/doi/full/10.1056/NEJMoa2034577">BNT162b2 mRNA vaccine</a> (NEJM)</li> <li><a href="https://www.microbe.tv/twiv/twiv-715-letters/">Letters read</a> on TWiV 715</li> <li>Timestamps by <a href= "http://www.twitter.com/jrrmicro">Jolene</a>. Thanks!</li> </ul> <h3 id="block-87e073be-38f1-4059-b3a9-7f9eb4c602e2" class= "block-editor-rich-text__editable block-editor-block-list__block wp-block is-selected rich-text" tabindex="0" role="group" contenteditable="true" aria-multiline= "true" aria-label="Block: Heading" data-block= "87e073be-38f1-4059-b3a9-7f9eb4c602e2" data-type="core/heading" data-title="Heading">Weekly Picks</h3> <p><strong>Brianne</strong> – <a href= "https://onlinelearning.hms.harvard.edu/hmx/immunity/">How the Body Reacts to Viruses</a><br /> <strong>Rich</strong> – <a