PubReading [303] - The Epigenomics of Cancer - P. Jones and S. Baylin

<p>Aberrant <strong>gene</strong> function and altered patterns of gene expression are key features of cancer. Growing evidence shows that acquired <strong>epigenetic</strong> abnormalities participate with genetic alterations to cause this dysregulation. Here, we review recent advances in understanding how epigenetic alterations participate in the earliest stages of neoplasia, including stem/ precursor cell contributions, and discuss the growing implications of these advances for strategies to control<strong> cancer</strong>.</p><p><em>DOI 10.1016/j.cell.2007.01.029 -2007</em></p>