Podcast 811: Ketamine for Pain

<p><strong>Contributor: Lessen, Aaron MD</strong></p> <p><strong>Educational Pearls:</strong></p> <ul> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Ketamine can be given at 0.2-0.3 mg/kg as subdissociative doses for pain control in the ED</span></li> <li style="list-style: none; display: inline"> <ul> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Ketamine coadministered with Haldol may reduce agitation</span></li> </ul> </li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">A recent study in Iran compared subdissociative Ketamine given with 2.5 mg Haldol to 1 mg/kg Fentanyl for pain control in the ED</span></li> <li style="list-style: none; display: inline"> <ul> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Ketamine with Haldol had better pain control than Fentanyl at 5, 10, 15 and 30 minutes </span></li> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Ketamine with Haldol less frequently required rescue medication </span></li> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Ketamine with Haldol did have increased agitation at only the 10 minute mark</span></li> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Of note, there was not a Ketamine only group to compare </span></li> </ul> </li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Ketamine with Haldol is a viable alternative combination for pain control </span></li> </ul> <p> </p> <p><strong>References</strong><strong><br /> <br /></strong></p> <p><span style="font-weight: 400;">Moradi MM, Moradi MM, Safaie A, Baratloo A, Payandemehr P. Sub dissociative dose of ketamine with haloperidol versus fentanyl on pain reduction in patients with acute pain in the emergency department; a randomized clinical trial.</span> <em><span style="font-weight: 400;">Am J Emerg Med</span></em><span style="font-weight: 400;">. 2022;54:16