Podcast 733: Nitric Oxide for COVID

<p><strong>Contributor: Nick Hatch, MD</strong></p> <p><strong>Educational Pearls:</strong></p> <ul> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Inhaled nitric oxide or Flolan may be considered in COVID</span></li> <li style="list-style: none; display: inline"> <ul> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Flolan is a prostaglandin can be inhaled or given IV</span></li> </ul> </li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">These medications are classically used for right-sided heart failure, but may be used in COVID</span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Causes pulmonary vasodilation to reduce the resistance against the right ventricle</span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Complications include hypotension and hemolysis, but nitric oxide can be turned off very quickly if needed</span></li> <li style="list-style: none; display: inline"> <ul> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Be careful and wean patients on nitric oxide for pulmonary hypertension</span></li> </ul> </li> </ul> <p><strong>References</strong></p> <p><span style="font-weight: 400;">Lotz C, Muellenbach RM, Meybohm P, et al. Effects of inhaled nitric oxide in COVID-19-induced ARDS - Is it worthwhile?. Acta Anaesthesiol Scand. 2021;65(5):629-632. doi:10.1111/aas.13757</span></p> <p><em><span style="font-weight: 400;">Summarized by John Spartz, MS4 | Edited by Erik Verzemnieks, MD</span></em></p> <p> </p> <p><span style="font-weight: 400;">The Emergency Medical Minute is excited to announce that we are now offering</span> <em><span style="font-weight: 400;">AMA PRA Category 1 credits™</span></em> <span style="font-weight: 400;">via online course modules. To access these and for more information, visit our website at</span> <a href= "https://emergencymedicalminute.org/cme-courses/"><span style= "font-weight: