Podcast 713: Oral Ketamine

<p><strong>Contributor: Don Stader, MD</strong></p> <p><strong>Educational Pearls:</strong></p> <ul> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Those on chronic opioid therapy may have high tolerance to opioids and/or opioid hyperalgesia</span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Ketamine is a good adjunct for pain control in patients on chronic opioid therapy</span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">To avoid the time constraints often required to push ketamine intravenously, it can be given orally:</span></li> <li style="list-style: none; display: inline;"> <ul> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Ketamine IV 25-50 mg (~0.01-0.03 mg/kg) as a single dose by mouth</span></li> </ul> </li> </ul> <p><strong>References</strong></p> <p><span style="font-weight: 400;">Blonk M, Koder B, et al. Use of oral ketamine in chronic pain management: A review. European Journal of Pain. 2009.</span></p> <p><span style="font-weight: 400;">Schwenk ES, et al. Consensus guidelines on the use of intravenous ketamine infusions for acute pain management from the America Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine and the American Society of Anesthesiologists. Reg Anesth Pain Med. 2018.</span></p> <p><em><span style="font-weight: 400;">Summarized by John Spartz, MS4 | Edited by Erik Verzemnieks, MD</span></em></p> <p> </p> <p><span style="font-weight: 400;">The Emergency Medical Minute is excited to announce that we are now offering</span> <em><span style="font-weight: 400;">AMA PRA Category 1 credits™</span></em> <span style="font-weight: 400;">via online course modules. To access these and for more information, visit our website at</span> <a href= "https://emergencymedicalminute.org/cme-courses/"><span style= "font-weight: 400;">https://emergencymedicalminute.org/cme-courses/</span></a> <span style="font-weight: 400;">and c