Podcast 644: Covid Outcomes

<p><strong>Contributor:  Aaron Lessen, MD</strong></p> <p><strong>Educational Pearls:</strong></p> <ul> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Meta-analysis of 57,420 COVID+ patients evaluated mortality after intubation</span></li> <li style="list-style: none; display: inline"> <ul> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">45% mortality rate for all patients in the study</span></li> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">84.4% mortality in patients over 80 years old</span></li> </ul> </li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">POSITIONED Trail assessed need for intubation in patients awake self-proning compared to not</span></li> <li style="list-style: none; display: inline"> <ul> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Risk of intubation and mortality was lower for those self-proning</span></li> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">0.3 hazard ratio for intubation in those self-proning</span></li> </ul> </li> </ul> <p><strong>References</strong></p> <p><span style="font-weight: 400;">Lim ZJ, Subramaniam A, Ponnapa Reddy M, et al. Case Fatality Rates for Patients with COVID-19 Requiring Invasive Mechanical Ventilation. A Meta-analysis. Am J Respir Crit Care Med. 2021;203(1):54-66. doi:10.1164/rccm.202006-2405OC</span></p> <p><span style="font-weight: 400;">Jagan N, Morrow LE, Walters RW, Klein LP, Wallen TJ, Chung J, Plambeck RW. The POSITIONED Study: Prone Positioning in Nonventilated Coronavirus Disease 2019 Patients-A Retrospective Analysis. Crit Care Explor. 2020 Oct 1;2(10):e0229. doi: 10.1097/CCE.0000000000000229. PMID: 33063033; PMCID: PMC7531752.</span></p> <p> </p> <p><em><span style="font-weight: 400;">Summarized by John Spartz, MS3 | Edited by Erik Verzemnieks, MD</span></em></p> <p><br /> <br /></p>