Podcast 641: Leadless Intracardiac Pacemaker

<p><strong>Contributor: Jared Scott, MD</strong></p> <p><strong>Educational Pearls:</strong></p> <ul> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Small capsule pacemaker (2.5 cm, 1 ml volume) resides in the heart without any associated wires or leads like a traditional pacemaker</span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">The new version has a 6 year battery life, after which it can be deactivated and a traditional pacemaker put in place</span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Cost is around 2-4 times that of a traditional pacemaker</span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">NEJM study from 2015 showed it met the primary efficacy endpoint in 90% of patients and the primary safety endpoint in 93.3% of patients</span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Follow up study showed 3% complication with the intracardiac pacemaker compared to 9% in traditional</span></li> </ul> <p><strong>References</strong></p> <p><span style="font-weight: 400;">Groner, Ashley PA-C; Grippe, Kristen PA-C The leadless pacemaker, Journal of the American Academy of Physician Assistants: June 2019 - Volume 32 - Issue 6 - p 48-50 doi: 10.1097/01.JAA.0000554750.85170.d4</span></p> <p><span style="font-weight: 400;">Reddy VY, Exner DV, Cantillon DJ, Doshi R, Bunch TJ, Tomassoni GF, Friedman PA, Estes NA 3rd, Ip J, Niazi I, Plunkitt K, Banker R, Porterfield J, Ip JE, Dukkipati SR; LEADLESS II Study Investigators. Percutaneous Implantation of an Entirely Intracardiac Leadless Pacemaker. N Engl J Med. 2015 Sep 17;373(12):1125-35. doi: 10.1056/NEJMoa1507192. Epub 2015 Aug 30. PMID: 26321198.</span></p> <p><span style="font-weight: 400;">Chan KH, McGrady M, Wilcox I. A Leadless Intracardiac Transcatheter Pacing System. N Engl J Med. 2016 Jun 30;374(26):2604. doi: 10.1056/NEJMc1604852. PMID: 27355553.</span></p> <p><em><span style="