Podcast 640: Kawasaki’s Disease

<p><strong>Contributor: Peter Bakes , MD</strong></p> <p><strong>Educational Pearls:</strong></p> <ul> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Pediatric Fever + Rash Differential: scarlet fever, measles, rubella, chicken pox, fifth’s disease, HHV-6, adenovirus, anaphylaxis, Kawasaki’s disease</span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Kawasaki’s is diagnosed clinically with prolonged fever (>7 days fever in <6 months > 5 days of fever >6 months with 4 of the following: </span></li> <li style="list-style: none; display: inline"> <ul> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Strawberry tongue/fissured lips</span></li> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Bilateral conjunctival injection</span></li> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Cervical lymphadenopathy</span></li> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Hand/foot edema</span></li> <li style="font-weight: 400;" aria-level="2"><span style= "font-weight: 400;">Maculopapular rash</span></li> </ul> </li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Can develop life threatening coronary artery aneurysms</span></li> <li style="font-weight: 400;" aria-level="1"><span style= "font-weight: 400;">Treated with aspirin/IVIG</span></li> </ul> <p><strong>References</strong></p> <p><span style="font-weight: 400;">Modesti AM, Plewa MC. Kawasaki Disease. [Updated 2020 Jul 2]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from:</span> <a href= "https://www.ncbi.nlm.nih.gov/books/NBK537163/?report=classic"><span style="font-weight: 400;"> https://www.ncbi.nlm.nih.gov/books/NBK537163/?report=classic</span></a></p> <p><span style="font-weight: 400;">Ramphul K, Mejias SG. Kawasaki disease: a comprehensive review. Arch Med Sci Atheroscler Dis. 2018;3:e41-e45. Publis