Podcast 575:  Light on the Sedation

<p><strong>Contributor: Aaron Lessen, MD</strong></p> <p><strong>Educational Pearls:</strong></p> <ul> <li style="font-weight: 400;"><span style= "font-weight: 400;">Studies have shown that patients who are under deeper sedation in the ICU have worse outcomes.</span></li> <li style="font-weight: 400;"><span style= "font-weight: 400;">Recent study compared lighter vs heavier sedation of patients in the emergency department receiving mechanical ventilation</span></li> <li style="font-weight: 400;"><span style= "font-weight: 400;">Patients receiving lighter sedation in the ED were often continued in the ICU</span></li> <li style="font-weight: 400;"><span style= "font-weight: 400;">Patients who had lighter sedation also tended to do better, meaning less days on the ventilator, less days in the ICU, and lower mortality supporting prior observations.</span></li> <li style="font-weight: 400;"><span style= "font-weight: 400;">Though purely observational, interesting suggestion that lighter sedation starting in the emergency department could have significant impact on important clinical outcomes</span></li> </ul> <p><strong>References</strong></p> <p><span style="font-weight: 400;">Fuller BM, Roberts BW, Mohr NM, et al. The ED-SED Study: A Multicenter, Prospective Cohort Study of Practice Patterns and Clinical Outcomes Associated With Emergency Department SEDation for Mechanically Ventilated Patients.</span> <em><span style="font-weight: 400;">Crit Care Med</span></em><span style="font-weight: 400;">. 2019;47(11):1539‐1548. doi:10.1097/CCM.0000000000003928</span></p> <p> </p> <p><em><span style="font-weight: 400;">Summarized by Jackson Roos, MS4 | Edited by Erik Verzemnieks, MD</span></em></p> <p><br /> <br /></p>