Managing teams and effective solutions to bridge nature and medicine

<p><span data-preserver-spaces="true">In this episode, Dr. Jeffery Gladden speaks with Colleen Cutcliffe, Ph.D., the Co-founder and CEO of Pendulum Therapeutics, she has an impressive background in leading and managing biology teams. She's a scientist with a Ph.D. in Biochemistry and Microbiology from Johns Hopkins University and has held senior positions at bioscience and pharmaceutical firms. Pendulum is passionate about finding revolutionary, safe, and practical solutions to ailments that can be tied to your gut, and they have a goal to bridge nature and medicine. In this episode, they talk about probiotics and what led Colleen down this particular path. They mention that there are critical pathways in our microbiome that need to be operational: fiber→, butyrate + mucin regulation. They also talk about Pendulum and the benefits of the products they offer, and how the ability to manage glucose response is fundamental to healthy aging. </span></p> <p> </p> <p><span data-preserver-spaces="true">Dr. Gladden introduces Colleen, and she introduces herself and how she got into what she does now. (1:30)</span></p> <p><span data-preserver-spaces="true">Colleen talks about how you could approach the microbiome using DNA sequencing data science. She also mentions that if you could marry DNA sequencing technologies and network data science with pharmaceutical drug development, you could, with the microbiome, create products that had the efficacy of a drug but the safety of a probiotic. (2:40)</span></p> <p><span data-preserver-spaces="true">Colleen mentioned a study that showed kids taking antibiotics before six months of age were also systematically more prone to obesity and type two diabetes as they age. Dr. Gladden mentions how antibiotics affect children. (4:00)</span></p> <p><span data-preserver-spaces="true">Colleen mentions how butyrate is a small molecule that's been known for quite some time to have a really important role in a variety of different things. She says it is probably one of the most interesting thing