Immune 64: A tangled web of wires

<p>Cindy, Steph, Brianne, and Vincent do a rapid review 11 immunology papers, including a wiring diagram for the immune system, group A streptococcus vaccines, systems immunology prediction of vaccines, class switch towards IgG4 after SARS-CoV-2 mRNA vaccination, very bad B cells, monoclonal antibody to two streptococcal M protein epitopes, transcriptional atlas of response to 13 vaccines, impact of SARS-CoV-2 exposure history on T cell and IgG response, neutrophilic inflammation predisposes to RSV infection, commensals avoiding recognition, and continuous germinal center invasion contributes to diversity of immune response.</p> <p>Hosts: <a href= "http://en.wikipedia.org/wiki/Vincent_Racaniello" target="_blank" rel="noreferrer noopener">Vincent Racaniello</a>, <a href= "https://twitter.com/cindyleifer">Cynthia Leifer</a>, <a href= "https://twitter.com/stephanielangel?lang=en">Steph Langel</a>, and <a href="http://www.twitter.com/BioProfBarker">Brianne Barker</a></p> <p>Subscribe (free): <a href= "https://podcasts.apple.com/us/podcast/immune/id1305309644" target= "_blank" rel="noreferrer noopener">Apple Podcasts</a>, <a href="https://www.google.com/podcasts?feed=aHR0cDovL2ltbXVuZS5saWJzeW4uY29tL3Jzcw%3D%3D" target="_blank" rel="noreferrer noopener">Google Podcasts</a>. <a href="http://immune.libsyn.com/rss" target= "_blank" rel="noreferrer noopener">RSS</a>, <a href= "http://eepurl.com/Gcw59" target="_blank" rel= "noreferrer noopener">email</a><br /> Become a <a href="https://www.microbe.tv/contribute" target= "_blank" rel= "noreferrer noopener">patron</a> of Immune!</p> <h3 id="links-for-this-episode">Links for this episode</h3> <ul> <li><a href="https://discord.gg/xA4JX7AeeU">MicrobeTV Discord Server</a></li> <li>Tangled <a title="" href= "https://www.nature.com/articles/s41586-022-05028-x">web of wires</a> (Nature)</li> <li>Path to group A <a title="" href= "https://academic.oup.com/cid/article/69/5/877/5280612?login=false"> <em>Streptococcus</em> vaccines</a> (Clin Inf Dis)</li> <li>Immune end-types <a title=