From Genotype to Phenotype: Leveraging functional genomics in oncology

<p>Drug discovery is increasingly informed by genomics, which can significantly boost the chances of a novel therapy successfully navigating the lengthy journey from bench to bedside. But despite the rapid proliferation of genomic information, we still have a limited understanding of how specific genes and genetic variations drive tumour growth and therapeutic resistance.</p> <p>In turn, this limits our ability to identify and validate novel targets that are truly informed by biology and make an impact on disease progression – arguably the most crucial step in the whole drug discovery pathway.</p> <p><em>By Dr Menelas Pangalos & Steve Rees et al.</em></p> <p><strong>If you'd like to view the original article then follow the link below:</strong></p> <p><a href= "https://www.ddw-online.com/therapeutics/p322917-from-genotype-to-phenotype:-leveraging-functional-genomics-in-oncology.html"> https://www.ddw-online.com/therapeutics/p322917-from-genotype-to-phenotype:-leveraging-functional-genomics-in-oncology.html</a></p> <p><strong>You can also download the original article pdf here:</strong></p> <p><a href= "https://www.ddw-online.com/media/32/136063/(3)-from-genotype-to-phenotype.pdf"> https://www.ddw-online.com/media/32/136063/(3)-from-genotype-to-phenotype.pdf</a></p> <p><strong>For more information on Drug Discovery World, head to:</strong></p> <p><a href= "https://www.ddw-online.com">https://www.ddw-online.com</a></p>