Episode 44 - Multi-system Inflammatory Syndrome in Children (MIS-C): An Interview with Dr. Ilene Claudius and Dr. Mohsen Saidinejad

<p> </p> <p class="MsoNormal">EMplify June 2020</p> <p class="MsoNormal">Multi-system Inflammatory Syndrome in Children (MIS-C) with COVID-19: An Interview with Dr. Ilene Claudius and Dr. Mohsen Saidinejad.</p> <ul> <li>What is it and when did we discover it as an entity? </li> <li>Have either of you treated anyone with the disease? </li> <li>Discussion of different cohorts of patients with MIS-C.</li> <li>Definition of MIS-C.</li> <li>Shock: cardiogenic and distributive shock presentations.</li> <li>Fever, is 4 days required?</li> <li>Discussion of where in the COVID-19 illness MIS-C occurs.</li> <li>Is clinical shock a requirement? </li> <li>Screening criteria (labs) and the Children’s Hospital Of Philadelphia pathway. </li> <li>What is available as treatment? <ul> <li>A discussion of IVIG</li> <li>Steroids</li> <li>Cytokine blockers</li> <li>Remdesivir</li> </ul> </li> <li>Why IVIG? </li> <li>Complications of the disease.</li> <li>Why are there more cases in New York? </li> <li>How has MIS-C changed your practice of testing children? </li> <li>Is there utility in testing for COVID-19 infection or antibodies in these cases?</li> </ul> <p> </p> <p>Resources:<a href="https://www.ebmedicine.net/topics/infectious-disease/COVID-19">EB Medicine Novel 2019 Coronavirus SARS-CoV-2 (COVID-19): An Updated Overview for Emergency Clinicians</a></p> <p class="MsoNormal"><a href="https://www.ebmedicine.net/topics/infectious-disease/COVID-19-Peds">EB Medicine COVID-19: The Impact on Pediatric Emergency Care</a></p> <p class="MsoNormal"><a href="https://www.chop.edu/clinical-pathway/multisystem-inflammatory-syndrome-mis-c-clinical-pathway">Children’s Hospital of Philadelphia Clinical Pathway for MIS-C.</a></p> <p class="MsoNormal">Have questions or comments on the podcast? Leave us a voicemail at 678-336-8466, ext 128 or write us at <a href="mailto:emplify@ebmedicine.net">emplify@ebmedicine.net</a> .</p> <p class="MsoNormal"> </p> <p class="MsoNormal"> </p> <p> </p>