October 22: Alec Baldwin discharged prop gun in incident that killed one on set. CDC issues guidance on booster shots. FBI confirms human remains found are Brian Laundrie’s. Queen Elizabeth “in good spirits” after spending night in hospital.

<p>Breaking news overnight: Alec Baldwin fires a prop gun while filming, killing the director of photography and wounding the director. Plus, the CDC gives the go-ahead for an added dose of protection for more Americans while also allowing for a mix-and-match approach — Savannah Guthrie speaks with  CDC director Dr. Rochelle Walensky about what comes next. Also ahead, FBI confirms those human remains found in a remote Florida nature preserve are those of Brian Laundrie. And, Buckingham Palace reveals that Queen Elizabeth has spent the night in a hospital before returning to Windsor Castle.</p>