APOL1 research and its impact on the African American population of renal patients with Reshma Kewalramani, MD, FASN

<p>APOL1-c is a kidney disorder associated with certain <em>APOL1</em> genetic mutations, often found in people of Western and Central African descent. The disease can lead to kidney cell injury, cell death and damage to the glomeruli, which filters blood in the kidney. This leads to abnormal amounts of protein in the urine and decreased kidney function.  </p> <p>Dr. Reshma Kewalramani, CEO of Vertex Pharmaceuticals discusses the company’s research into the underlying cause of APOL1-mediated kidney disease.</p>